β-CGRP, human TFA (101462-82-2 free base)
CAS No.
β-CGRP, human TFA (101462-82-2 free base) ( Human β-CGRP (TFA); CGRP-II (Human) (TFA) )
Catalog No. M29830 CAS No.
β-CGRP,human tissue is one of the calcitonin peptide, through complex behavior of calcitonin receptor like receptor (CRLR) - and receptor activity - modifying proteins (increased), and 1 and 300 - nM CRLR IC50s/RAMP1 and CRLR/RAMP2 cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Nameβ-CGRP, human TFA (101462-82-2 free base)
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NoteResearch use only, not for human use.
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Brief Descriptionβ-CGRP,human tissue is one of the calcitonin peptide, through complex behavior of calcitonin receptor like receptor (CRLR) - and receptor activity - modifying proteins (increased), and 1 and 300 - nM CRLR IC50s/RAMP1 and CRLR/RAMP2 cells.
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Descriptionβ-CGRP,human tissue is one of the calcitonin peptide, through complex behavior of calcitonin receptor like receptor (CRLR) - and receptor activity - modifying proteins (increased), and 1 and 300 - nM CRLR IC50s/RAMP1 and CRLR/RAMP2 cells.(In Vitro):β-CGRP, human is one of calcitonin peptides, acts via complex of calcitonin-receptor-like receptor (CRLR) and receptor-activity-modifying protein (RAMP), with IC50s of 1 nM in both SK-N-MC and Swiss 3T3 cells express CRLR and RAMP1, and 130 nM and 300 nM in NG108-15 and HEK293T cells expressing CRLR and RAMP2. CGRP is a potent vasodilator and also shows pro- and -anti-inflammatory activity.
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SynonymsHuman β-CGRP (TFA); CGRP-II (Human) (TFA)
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PathwayOthers
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TargetOther Targets
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RecptorIC50: 1 nM (CRLR/RAMP1, cell assay), 300 nM (CRLR/RAMP2, cell assay)
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Research Area——
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Indication——
Chemical Information
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CAS Number--
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Formula Weight3907.4
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Molecular FormulaC164H268F3N51O50S3
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Purity>98% (HPLC)
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SolubilityH2O : ≥ 50 mg/mL (12.80 mM)
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SMILES——
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Chemical Name
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
McLatchie LM, et al. RAMPs regulate the transport and ligand specificity of the calcitonin-receptor-like receptor. Nature. 1998 May 28;393(6683):333-9.
molnova catalog
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